Description

4-Methoxybenzoylacetonitrile is a versatile aromatic ketone derivative and a key synthetic intermediate in organic chemistry. Its molecular structure, featuring both a methoxybenzoyl group and a reactive nitrile, makes it a valuable building block for the synthesis of more complex heterocyclic and pharmaceutical compounds. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including potential anti-inflammatory, antimicrobial, and central nervous system (CNS) active agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its aromatic backbone for bioactive molecule construction.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and advanced organic materials requiring specific photochemical or electronic properties.
• Heterocyclic Chemistry: Employed in the formation of pyrazoles, isoxazoles, and other nitrogen-containing heterocycles, which are privileged scaffolds in medicinal chemistry.
• Chemical Research: Used in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways.
• Ligand and Complex Synthesis: Can be utilized to prepare chelating ligands for metal-organic frameworks (MOFs) or catalytic complexes.

Basic Information

Product Name	4-Methoxybenzoylacetonitrile
CAS No.	3672-47-7
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	1-(4-Methoxyphenyl)-2-cyanoethanone; p-Methoxybenzoylacetonitrile; 4-Methoxy-ω-cyanacetophenone; 2-Cyano-1-(4-methoxyphenyl)ethanone; 4-Methoxybenzyl cyanide ketone; Acetonitrile, (4-methoxybenzoyl)-; NSC 403119
EINECS	222-943-5

Quality Control

Our 4-Methoxybenzoylacetonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.