Description

n-Acetylglycyl-Histidyl-Glycine is a synthetic tripeptide derivative, specifically an acetylated form of the glycyl-histidyl-glycine sequence. This compound is valued for its role as a biochemical precursor and research tool in the study of peptide function and metal ion coordination. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in biochemical research, pharmaceutical development, and as a potential intermediate for more complex bioactive peptides.

Application

• Biochemical Research: Used as a model peptide in studies of enzyme kinetics, protein folding, and peptide-metal interactions.
• Pharmaceutical Intermediates: Serves as a key building block or precursor in the synthesis of more complex therapeutic peptides and peptidomimetics.
• Cosmetic Peptide Synthesis: Investigated for potential use as an intermediate in the production of anti-aging or skin-conditioning peptide actives.
• Chelation Studies: Employed in research focused on metal ion chelation and transport due to the histidine residue's imidazole side chain.
• Cell Culture & Diagnostics: May be used in specialized cell culture media formulations or as a component in diagnostic assay development.

Basic Information

Product Name	n-Acetylglycyl-Histidyl-Glycine
CAS No.	3654-95-3
Molecular Formula	C13H19N5O5
Molecular Weight	325.32 g/mol
Synonyms	Acetyl-Gly-His-Gly; Ac-Gly-His-Gly-OH; N-Acetyl-Gly-His-Gly; Glycyl-L-histidylglycine acetate; L-Histidylglycine, N-acetyl-; GHK Acetate (common reference); Copper Peptide GHK precursor; 2-Acetamido-N-[2-[[1-(2-amino-2-oxoethyl)-4-imidazolyl]methylamino]-2-oxoethyl]acetamide
EINECS	Contact for details

Quality Control

Our n-Acetylglycyl-Histidyl-Glycine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.