Description

Lithium Dimethylamide is a highly reactive organolithium compound and a powerful non-nucleophilic base. Its primary value lies in its ability to deprotonate a wide range of weakly acidic substrates, including ketones, esters, and amides, without participating in nucleophilic addition reactions. This makes it an indispensable reagent for synthetic chemists in the pharmaceutical, agrochemical, and advanced materials industries, particularly for the generation of enolates and other carbanions under mild conditions.

Application

• As a strong, non-nucleophilic base for the deprotonation of carbon acids in organic synthesis.
• Generation of enolates from ketones, esters, and amides for subsequent alkylation or aldol reactions.
• Key reagent in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Used in polymer chemistry for initiating anionic polymerization or modifying polymer chains.
• Catalyst or base in the production of specialty chemicals and fine chemicals.
• Research and development applications in academic and industrial laboratories for novel bond-forming methodologies.

Basic Information

Product Name	Lithium Dimethylamide
CAS No.	3585-33-9
Molecular Formula	C2H6LiN
Molecular Weight	51.01 g/mol
Synonyms	Lithium Dimethylamide; Lithium Bis(dimethylamide); N-Lithiodimethylamine; Dimethylaminolithium; LiN(CH3)2; Lithium Dimethylamidure; Lithium dimethylamido complex; LDA (commonly, though LDA typically refers to Lithium Diisopropylamide)
EINECS	Contact for details

Quality Control

Our Lithium Dimethylamide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We adhere to relevant industry standards for organometallic reagents. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat and moisture sources. Due to its hygroscopic and pyrophoric nature, handle only under inert conditions. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or suspension
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Lithium Content	Contact for details
Solvent Content (if supplied as a solution)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.