Description

n-Heptadecanoyl Coenzyme A Lithium Salt is a high-purity, long-chain fatty acyl-CoA ester derivative, a critical biochemical reagent for in vitro enzymatic studies. This compound serves as a specific substrate for investigating the metabolism of odd-chain fatty acids, which are of growing interest in metabolic research and lipidomics. It is essential for researchers and manufacturers in biochemical research, pharmaceutical development, and diagnostic enzyme assay production who require reliable, well-characterized coenzyme A derivatives.

Application

• Enzymology Research: As a defined substrate for studies on acyl-CoA synthetases, dehydrogenases, and other enzymes involved in fatty acid β-oxidation, particularly for odd-chain fatty acid pathways.
• Metabolic Pathway Analysis: Used in cell-free systems and mitochondrial preparations to trace the metabolism of heptadecanoic acid and its intermediates.
• Diagnostic Kit Manufacturing: A key component in the formulation of clinical diagnostic kits for measuring specific enzyme activities related to lipid metabolism disorders.
• Pharmaceutical R&D: Employed in screening and characterization of potential drug candidates targeting metabolic enzymes like the peroxisomal acyl-CoA oxidase family.
• Biomarker Studies: Useful in the synthesis and study of lipid-based biomarkers and in calibrating mass spectrometry-based lipidomic platforms.
• Biocatalyst Development: Serves as a substrate for engineering and testing novel enzymes for biocatalytic synthesis of specialized lipids.

Basic Information

Product Name	n-Heptadecanoyl Coenzyme A Lithium Salt
CAS No.	3546-17-6
Molecular Formula	C38H66N7O17P3S • xLi
Molecular Weight	~1058.9 (Free acid)
Synonyms	Heptadecanoyl-CoA Lithium Salt; Margaroyl-Coenzyme A Lithium Salt; C17:0-CoA Lithium Salt; Coenzyme A, S-heptadecanoate, lithium salt; n-Heptadecanoyl-CoA Li+; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[[2-[(1-oxoheptadecyl)thio]ethyl]amino]propyl]amino]butyl] dihydrogen diphosphate) lithium salt; Margaroyl-CoA Lithium Salt
EINECS	Contact for details

Quality Control

Our n-Heptadecanoyl Coenzyme A Lithium Salt is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the exacting standards required for life science research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90% (of theoretical)
Water Content (KF)	≤ 5%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.