Description

2-Chloro-10-[3-(Methylamino)Propyl]-10H-Phenothiazin-7-Ol is a key phenothiazine derivative with significant pharmaceutical relevance. This compound serves as a crucial intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in the development of psychotropic and antihistaminic drugs. It is primarily required by fine chemical manufacturers and R&D laboratories in the global pharmaceutical and life sciences sectors for producing high-value therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of phenothiazine-based antipsychotic and neuroleptic APIs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new central nervous system (CNS) agents.
• Fine Chemical Synthesis: Serves as a precursor for manufacturing specialized chemicals with tricyclic phenothiazine cores.
• Reference Standard: Employed as an analytical standard in quality control laboratories for drug substance identification and purity assessment.

Basic Information

Product Name	2-Chloro-10-[3-(Methylamino)Propyl]-10H-Phenothiazin-7-Ol
CAS No.	3546-08-5
Molecular Formula	C₁₆H₁₇ClN₂OS
Molecular Weight	320.84 g/mol
Synonyms	7-Hydroxy-2-chloro-10-(3-methylaminopropyl)phenothiazine; 2-Chloro-10-(3-methylaminopropyl)phenothiazin-7-ol; N-Methyl-3-(2-chloro-7-hydroxyphenothiazin-10-yl)propylamine; 3546-08-5; Phenothiazin-7-ol, 2-chloro-10-[3-(methylamino)propyl]-10H-
EINECS	Contact for details

Quality Control

Our 2-Chloro-10-[3-(Methylamino)Propyl]-10H-Phenothiazin-7-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.