Description

4-Aminophenylacetonitrile Hydrochloride is a versatile aromatic amine hydrochloride salt that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a protected amine and reactive nitrile group, enabling efficient construction of complex heterocyclic and pharmaceutical intermediates. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phenethylamine or benzylamine backbones.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators that require aniline-derived structures.
• Dye and Pigment Manufacturing: Serves as a starting material for azo dyes and other colorants where amino functionality is necessary for chromophore development.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel chemical entities.
• Liquid Crystal & Electronic Material Precursor: Used in the synthesis of advanced materials for display technologies and organic electronics.

Basic Information

Product Name	4-Aminophenylacetonitrile Hydrochloride
CAS No.	3457-99-6
Molecular Formula	C8H9N2•HCl
Molecular Weight	168.63 g/mol (Free base: 132.17 g/mol)
Synonyms	4-Aminobenzyl cyanide hydrochloride; (4-Aminophenyl)acetonitrile hydrochloride; p-Aminophenylacetonitrile HCl; 4-Aminobenzeneacetonitrile hydrochloride; 2-(4-Aminophenyl)acetonitrile hydrochloride; α-Amino-p-tolunitrile hydrochloride; 4-Cyanobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Aminophenylacetonitrile Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.