Description

n-Boc Aniline is a crucial protected aniline derivative, serving as a versatile and stable building block in organic synthesis. Its primary value lies in the tert-butoxycarbonyl (Boc) group, which effectively masks the reactive amine functionality, allowing for selective reactions elsewhere on the molecule during multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of complex molecules, peptides, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing aromatic amine motifs.
• Peptide Synthesis: Used as a protected amine precursor in solid-phase and solution-phase peptide chemistry.
• Agrochemical Production: Intermediate in the manufacture of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis & Research: Fundamental reagent for constructing complex organic architectures, including heterocycles and functionalized aromatics in academic and industrial R&D.
• Material Science: Monomer or precursor for polymers, dyes, and advanced functional materials.
• Chemical Derivatization: Used to introduce the Boc-protected aniline group into larger molecules for further chemical manipulation.

Basic Information

Product Name	n-Boc Aniline
CAS No.	3422-01-3
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	tert-Butyl N-phenylcarbamate; N-(tert-Butoxycarbonyl)aniline; N-Boc-aniline; BOC-Aniline; Aniline, N-BOC-protected; Carbamic acid, N-phenyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl phenylcarbamate; tert-Butyl phenylcarbamate
EINECS	222-316-7

Quality Control

Our n-Boc Aniline is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to relevant industry standards and can support requirements for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	134 - 138 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.