Description

Methyl L-Tyrosinate Hydrochloride is a protected derivative of the essential amino acid L-Tyrosine, widely used as a key chiral building block in organic synthesis. This high-purity compound is critical for ensuring stereochemical integrity and yield in complex peptide and pharmaceutical manufacturing processes. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and advanced biomolecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of peptide-based drugs, hormone analogs, and complex bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected tyrosine residue to prevent unwanted side reactions.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway research, and proteomics.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development and quality control in QC/QA laboratories.
• Fine Chemical Production: A building block for manufacturing specialty chemicals, advanced materials, and custom synthesis projects.

Basic Information

Product Name	Methyl L-Tyrosinate Hydrochloride
CAS No.	3417-91-2
Molecular Formula	C10H14ClNO3
Molecular Weight	231.68 g/mol
Synonyms	L-Tyrosine methyl ester hydrochloride; (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid methyl ester hydrochloride; Methyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride; Methyl L-tyrosinate HCl; H-Tyr-OMe·HCl; Tyrosine methyl ester HCl; Methyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl L-Tyrosinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, ensuring compliance with relevant industry standards for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	+8.0° to +10.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.