Description

1-Chloro-4-Nonyne is a versatile aliphatic building block featuring both a terminal alkyne and a reactive chloroalkyl group. This bifunctional nature makes it a valuable intermediate for constructing complex molecular architectures through selective cross-coupling and click chemistry reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of new active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira and other palladium-catalyzed couplings.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require specific alkyne-containing side chains.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functional surfaces with tailored properties.
• Liquid Crystal & OLED Materials: Employed in the synthesis of advanced organic electronic materials and liquid crystal compounds where molecular rigidity and functional group alignment are critical.
• Bioconjugation & Probe Development: The terminal alkyne group is ideal for copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the labeling of biomolecules for diagnostics and research.
• Organic Synthesis Building Block: Provides a flexible carbon chain for modular synthesis in medicinal and process chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Chloro-4-Nonyne
CAS No.	3416-74-8
Molecular Formula	C9H15Cl
Molecular Weight	158.67 g/mol
Synonyms	4-Nonyn-1-yl chloride; 1-Chloro-4-nonyne; 4-Nonynyl chloride; Non-4-yn-1-yl chloride; 1-Chloronon-4-yne; Chlorononyne; (4-Nonynyl)chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Nonyne is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.