Description

3,4-Dehydro-Dl-Proline is a non-proteinogenic proline derivative characterized by a double bond within its pyrrolidine ring. This structural feature makes it a valuable synthetic intermediate and building block in organic and medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel compounds, including peptidomimetics and enzyme inhibitors.

Application

• Pharmaceutical Research & Development: Serves as a key chiral building block for synthesizing novel drug candidates and bioactive peptides.
• Peptidomimetic Design: Used to introduce conformational constraints into peptide backbones, enhancing stability and biological activity.
• Chemical Biology Probes: Employed in the synthesis of probes to study enzyme mechanisms, particularly those involving proline metabolism.
• Organic Synthesis Intermediate: Acts as a precursor for more complex heterocyclic compounds and fine chemicals.
• Academic Research: Utilized in universities and research institutes for methodological studies in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	3,4-Dehydro-Dl-Proline
CAS No.	3395-35-5
Molecular Formula	C5H7NO2
Molecular Weight	113.11 g/mol
Synonyms	3,4-Didehydro-DL-proline; (DL)-3,4-Dehydroproline; 2-Pyrroline-2-carboxylic acid; 3,4-Dehydroproline, DL-; δ3,4-Dehydro-DL-proline; 1-Aza-1,3-butadiene-2-carboxylic acid, 2,3-dihydro-; 3,4-Dehydro-2-carboxypyrrolidine
EINECS	Contact for details

Quality Control

Our 3,4-Dehydro-Dl-Proline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.