Description

Z-Gly-Trp-Oh is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of the glycyl-tryptophan sequence. This compound is a critical intermediate in the synthesis of more complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry research, and the development of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of custom peptides.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and proteomics research.
• Pharmaceutical Intermediate: A building block in the multi-step synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Combinatorial Chemistry Libraries: Employed to create diverse arrays of compounds for high-throughput screening.
• Academic Research: Used in university and institutional labs for teaching advanced peptide chemistry and conducting fundamental research.

Basic Information

Product Name	Z-Gly-Trp-Oh
CAS No.	3392-19-6
Molecular Formula	C21H21N3O5
Molecular Weight	395.41 g/mol
Synonyms	N-Carbobenzoxy-glycyl-L-tryptophan; N-Cbz-Gly-L-Trp-OH; Z-Gly-L-Trp-OH; Z-Gly-Trp; Cbz-Gly-Trp-OH; Benzyloxycarbonylglycyltryptophan; N-[(Benzyloxy)carbonyl]glycyl-L-tryptophan; Nα-Cbz-glycyl-L-tryptophan
EINECS	Contact for details

Quality Control

Our Z-Gly-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	-10.0° to -15.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.