Description

Boc-Leu-Onp is a specialized amino acid derivative widely used as a key building block in peptide synthesis. This compound is crucial for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals and bioactive peptides. It is particularly valuable for the pharmaceutical, biotechnology, and academic research sectors where precise molecular construction is paramount.

Application

• Key intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Building block for the synthesis of complex peptides and peptidomimetics with leucine residues.
• Research and development of novel therapeutic peptides and APIs (Active Pharmaceutical Ingredients).
• Production of custom peptides for biochemical and pharmacological studies.
• Used in the preparation of peptide libraries for drug discovery and screening.
• Intermediate in the synthesis of peptide-based diagnostics and biomarkers.

Basic Information

Product Name	Boc-Leu-Onp
CAS No.	3350-19-4
Molecular Formula	C₁₇H₂₄N₂O₆
Molecular Weight	352.38 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-leucine 4-nitrophenyl ester; Boc-L-leucine p-nitrophenyl ester; Boc-Leu-ONp; N-Boc-L-leucine 4-nitrophenyl ester; tert-Butyloxycarbonyl-L-leucine p-nitrophenyl ester; (S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid 4-nitrophenyl ester; BOC-Leu-ONP; Boc-Leu-OpNP
EINECS	Contact for details

Quality Control

Our Boc-Leu-Onp is manufactured under strict quality control protocols to ensure high chemical purity and consistency. Each batch is analyzed to meet rigorous specifications suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-15° to -20° (c=1 in DMF)
Melting Point	82°C - 86°C
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Solubility	Soluble in DMF, DMSO; slightly soluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.