Description

D-Aldosterone 18,21-Diacetate is a key acetylated derivative of the primary mineralocorticoid hormone, aldosterone. This compound is of significant value as a high-purity reference standard and pharmaceutical intermediate in advanced research and development. It is primarily required by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in steroid hormone research, metabolic studies, and the synthesis of specialized biochemical reagents.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, LC-MS) and for method validation in quality control laboratories.
• Biochemical Research: Serves as a critical intermediate or substrate in studies investigating the renin-angiotensin-aldosterone system (RAAS) and mineralocorticoid receptor activity.
• Metabolite Synthesis: Employed in the synthesis of aldosterone metabolites and related steroid analogs for pharmacological profiling.
• Diagnostic Kit Development: Utilized as a raw material in the development of immunoassays and diagnostic tests for hormonal disorders.
• Academic & Institutional Research: Provides a well-defined chemical entity for fundamental research in endocrinology and steroid chemistry.

Basic Information

Product Name	D-Aldosterone 18,21-Diacetate
CAS No.	3329-79-1
Molecular Formula	C₂₅H₃₄O₇
Molecular Weight	446.53 g/mol
Synonyms	Aldosterone 18,21-Diacetate; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al 18,21-diacetate; 18,21-Diacetoxy-11β-hydroxy-3,20-dioxopregn-4-en-18-al; Aldosterone Diacetate; 18,21-Di-O-acetylaldosterone; 11β-Hydroxy-3,20-dioxopregn-4-ene-18,21-dial 18,21-diacetate
EINECS	Contact for details

Quality Control

Our D-Aldosterone 18,21-Diacetate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.