Description

2-Amino-3-Pentafluorophenyl-Propionic Acid is a specialized fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its unique pentafluorophenyl group imparts distinct electronic and steric properties, making it invaluable for modulating the biological activity and physicochemical characteristics of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Peptide Modification: Used to incorporate fluorinated aromatic side chains into synthetic peptides, enhancing their metabolic stability, lipophilicity, and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Employed in the design of specialized ligands for catalysis and molecular recognition applications in asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of fluorinated polymers and advanced organic materials with unique surface properties and stability.
• Bioconjugation & Probe Synthesis: Acts as a versatile handle for creating fluorescent probes, affinity labels, and other bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	2-Amino-3-Pentafluorophenyl-Propionic Acid
CAS No.	3321-96-8
Molecular Formula	C9H6F5NO2
Molecular Weight	255.14 g/mol
Synonyms	3-Amino-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid; 2-Amino-3-(pentafluorophenyl)propionic acid; Pentafluorophenylalanine; F5-Phe; 3-(Pentafluorophenyl)-β-alanine; (R,S)-2-Amino-3-(pentafluorophenyl)propanoic acid; DL-2-Amino-3-(pentafluorophenyl)propionic acid; β-(Pentafluorophenyl)alanine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Pentafluorophenyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Optical Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.