Description

Testosterone-1,2-T2, Acetate-1-14C is a radiolabeled derivative of testosterone acetate, specifically labeled with carbon-14 at the acetate moiety. This compound is a critical tool for advanced metabolic and pharmacokinetic studies, enabling precise tracking of hormone pathways in biological systems. It is primarily utilized by research institutions, pharmaceutical R&D departments, and contract research organizations (CROs) specializing in endocrinology, steroid metabolism, and drug development.

Application

• Tracer Studies in Steroid Metabolism: Used as a radioactive tracer to investigate the metabolic fate, biotransformation, and excretion pathways of testosterone and its esters in vivo and in vitro.
• Drug Discovery & Development: Essential for absorption, distribution, metabolism, and excretion (ADME) studies of new androgen receptor-targeting pharmaceuticals.
• Biochemical Research: Serves as a labeled substrate for studying enzyme kinetics, receptor binding assays, and the biochemical mechanisms of androgen action.
• Environmental & Doping Analysis: Can be employed as an internal standard or reference material in sophisticated analytical methods like LC-MS for detecting steroid abuse or environmental contaminants.
• Manufacturing Process Validation: Used in pharmaceutical manufacturing for process validation and quality control of testosterone-based products.

Basic Information

Product Name	Testosterone-1,2-T2, Acetate-1-14C
CAS No.	3268-78-8
Molecular Formula	C21H28O3 (with ¹⁴C label)
Molecular Weight	~330.45 g/mol (unlabeled)
Synonyms	Testosterone Acetate-1-¹⁴C; [1-¹⁴C]Acetoxy-4-androsten-17β-ol-3-one; 17β-Hydroxyandrost-4-en-3-one 1-¹⁴C-acetate; Androst-4-en-17β-ol-3-one acetate-1-¹⁴C; Radiolabeled Testosterone Acetate; Carbon-14 Labeled Testosterone Acetate; [¹⁴C]-Testosterone Acetate
EINECS	Contact for details

Quality Control

Every batch of Testosterone-1,2-T2, Acetate-1-14C is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to ensure identity, purity, and specific activity. Certificates of Analysis (COA) are supplied with each shipment, detailing parameters such as radiochemical purity (by HPLC), specific activity, and chemical purity. Our production adheres to cGMP principles where applicable, supporting regulatory submissions for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures of 2-8°C or as specified on the label. This product is light-sensitive and should be stored away from light. For long-term storage, solutions should be kept at or below -20°C. Always handle radioactive materials in accordance with local and international radiation safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95% (Chemical Purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied as solution)	Benzene, Ethanol, or Toluene (as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.