Description

Ethyl 2-Methyl-4,5,6,7-Tetrafluorobenzofuran-3-Carboxylate is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique tetrafluorobenzofuran scaffold, which is crucial for modulating the physicochemical properties of target molecules, such as lipophilicity, metabolic stability, and bioavailability. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for fluorinated organic electronic materials, such as semiconductors or light-emitting compounds.
• Chemical Biology Probe Development: Utilized to create fluorinated analogs of natural products or biochemical tools for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex fluorinated architectures.

Basic Information

Product Name	Ethyl 2-Methyl-4,5,6,7-Tetrafluorobenzofuran-3-Carboxylate
CAS No.	3265-71-2
Molecular Formula	C₁₂H₈F₄O₃
Molecular Weight	276.19 g/mol
Synonyms	Ethyl 2-methyl-4,5,6,7-tetrafluoro-1-benzofuran-3-carboxylate; 4,5,6,7-Tetrafluoro-2-methylbenzofuran-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-2-methyl-4,5,6,7-tetrafluorobenzofuran; 2-Methyl-4,5,6,7-tetrafluorobenzofuran-3-carboxylic acid ethyl ester; Ethyl 2-methyl-4,5,6,7-tetrafluorobenzofurane-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Methyl-4,5,6,7-Tetrafluorobenzofuran-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.