Description

Benzylpenicillenic Acid is a key chemical intermediate and degradation product derived from penicillin G. This compound is of significant importance in pharmaceutical research and development, particularly for studying penicillin allergy mechanisms and as a precursor for specialized syntheses. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in antibiotic research, immunology studies, and the development of diagnostic reagents.

Application

• Pharmaceutical Research: Critical intermediate in the study of penicillin degradation pathways and the synthesis of penicillin derivatives.
• Immunology & Allergy Studies: Used as a hapten or model compound for investigating the mechanisms of penicillin-induced allergic reactions and hypersensitivity.
• Analytical Reference Standard: Serves as a high-purity standard in HPLC, LC-MS, and other chromatographic methods for quality control and impurity profiling of penicillin-based pharmaceuticals.
• Biochemical Research: Employed in enzymatic studies and as a substrate for investigating β-lactamase activity and resistance mechanisms.
• Diagnostic Reagent Development: Used in the development and calibration of diagnostic tests for penicillin allergy.
• Organic Synthesis: Acts as a specialized building block for the synthesis of novel β-lactam compounds and other complex molecules.

Basic Information

Product Name	Benzylpenicillenic Acid
CAS No.	3264-88-8
Molecular Formula	C16H18N2O5S
Molecular Weight	350.39 g/mol
Synonyms	Penicillenic Acid; Benzylpenicillenic Acid; (2Z)-2-[[(2R)-2-Amino-2-phenylacetyl]amino]-5,5-dimethyl-4,5-dihydro-1,3-thiazole-4-carboxylic Acid; Penicillenic Acid (Benzyl); 4-Thiazolidinecarboxylic acid, 2-[[(2R)-2-amino-2-phenylacetyl]amino]-5,5-dimethyl-, (2Z)-; Benzylpenicillenic acid (major penicillin allergen); BPenicillenic acid
EINECS	221-882-3

Quality Control

Our Benzylpenicillenic Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and impurity profiling to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.