Description

Z-Ala-Phe-OMe is a protected dipeptide derivative, widely utilized as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It serves the needs of the pharmaceutical, biotechnology, and academic research sectors, particularly in the development of active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of therapeutic peptides.
• Biochemical Research: Used in studies of enzyme-substrate interactions, particularly with proteases like chymotrypsin, due to the specific cleavage site.
• API Development: Employed in the research and development stages for creating novel peptide-based drugs and diagnostics.
• Custom Peptide Synthesis: A fundamental reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) producing custom peptide sequences for clients.
• Academic Studies: Serves as a standard or model compound in graduate-level organic chemistry and biochemistry laboratories for teaching peptide coupling and deprotection techniques.

Basic Information

Product Name	Z-Ala-Phe-OMe
CAS No.	3235-14-1
Molecular Formula	C21H24N2O5
Molecular Weight	384.43 g/mol
Synonyms	N-Carbobenzoxy-L-alanyl-L-phenylalanine methyl ester; Z-L-Ala-L-Phe-OMe; Z-Ala-Phe-OMe; Cbz-Ala-Phe-OMe; Nα-Cbz-L-alanyl-L-phenylalanine methyl ester; Benzyloxycarbonyl-L-alanyl-L-phenylalanine methyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid; (S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amide; L-Alanine, N-[(phenylmethoxy)carbonyl]-, (1S)-1-[[(1S)-1-methoxy-1-oxo-3-phenyl-2-propanyl]amino]carbonyl]ethyl ester
EINECS	221-787-7

Quality Control

Our Z-Ala-Phe-OMe is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.