Description

(S)-2-Amino-3-(4-Hydroxy-3-Nitro-Phenyl)-Propionic Acid Methyl Ester CAS NO 3195-65-1 is a high-purity, chiral amino acid derivative featuring a nitro-substituted phenolic ring, making it a critical building block for advanced synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and functional group diversity in their molecular designs. It is primarily utilized in pharmaceutical R&D for the synthesis of novel active pharmaceutical ingredients (APIs) and in agrochemical research for developing new crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides and pesticides, where specific chirality can enhance efficacy and reduce environmental impact.
• Peptide Mimetics & Drug Discovery: Serves as a constrained, non-natural amino acid analog for constructing peptide-based libraries and probing structure-activity relationships (SAR).
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in stereoselective transformations.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and material science research.

Basic Information

Product Name	(S)-2-Amino-3-(4-Hydroxy-3-Nitro-Phenyl)-Propionic Acid Methyl Ester
CAS No.	3195-65-1
Molecular Formula	C10H12N2O5
Molecular Weight	240.21 g/mol
Synonyms	L-3-(4-Hydroxy-3-nitrophenyl)alanine methyl ester; Methyl (S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoate; (S)-Methyl 2-amino-3-(4-hydroxy-3-nitrophenyl)propionate; L-4-Hydroxy-3-nitrophenylalanine methyl ester; (S)-3-(4-Hydroxy-3-nitro-phenyl)-alanine methyl ester; H-3-(4-OH-3-NO2-Phe)-OMe; (S)-2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-(4-Hydroxy-3-Nitro-Phenyl)-Propionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.