Description

2-Cyclopropylbenzonitrile is a versatile aromatic nitrile building block featuring a cyclopropyl substituent. This molecular architecture is crucial for synthesizing advanced pharmaceutical intermediates and agrochemicals, where the cyclopropyl group is a key pharmacophore known to modulate biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the cyclopropyl moiety enhances efficacy.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors and liquid crystals due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Cyclopropylbenzonitrile
CAS No.	3154-99-2
Molecular Formula	C10H9N
Molecular Weight	143.19 g/mol
Synonyms	o-Cyclopropylbenzonitrile; 2-Cyanophenylcyclopropane; Benzonitrile, 2-cyclopropyl-; (2-Cyanophenyl)cyclopropane; 2-Cyclopropybenzencarbonitrile; 1-Cyano-2-cyclopropylbenzene
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.