Description

Myristoyl Coenzyme A Monohydrate is a high-purity biochemical reagent essential for studying lipid metabolism and enzyme function. This compound serves as a critical substrate for investigating fatty acid oxidation, biosynthesis, and the regulation of key metabolic pathways like β-oxidation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for enzymatic assays, metabolic research, and as a reference standard.

Application

• Enzymatic Research & Assay Development: As a specific substrate for acyl-CoA dehydrogenases, synthetases, and other enzymes involved in fatty acid metabolism.
• Metabolic Pathway Studies: Investigating β-oxidation, lipid biosynthesis, and mitochondrial function in cellular and biochemical models.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) assays to identify potential drug candidates targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for measuring specific enzyme activities related to metabolic health.
• Biochemical Reference Standard: Serves as a pure calibrant in analytical methods such as HPLC and mass spectrometry for quantitative analysis.
• Nutritional & Metabolic Disease Research: Studying the role of medium-chain fatty acid metabolism in conditions like obesity, diabetes, and cardiovascular diseases.

Basic Information

Product Name	Myristoyl Coenzyme A Monohydrate
CAS No.	3130-72-1
Molecular Formula	C35H64N7O17P3S • H2O
Molecular Weight	977.89 g/mol (Anhydrous: 959.88 g/mol)
Synonyms	Myristoyl-CoA; Tetradecanoyl-CoA; Coenzyme A, S-tetradecanoate; Tetradecanoyl-coenzyme A; Myristoyl CoA; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[[2-(tetradecanoylsulfanyl)ethyl]amino]propyl]amino]butyl] dihydrogen diphosphate); S-Tetradecanoylcoenzyme A; NSC 334368
EINECS	221-522-4

Quality Control

Our Myristoyl Coenzyme A Monohydrate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research and in-vitro diagnostic use. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be sealed under dry nitrogen or argon after each use and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	3.0 - 6.0 %
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.