Description

Bromocyanoacetylene is a highly reactive bifunctional organic building block, combining both bromo and cyano substituents on an acetylene core. This unique structure makes it a valuable synthon for constructing complex heterocyclic and pharmaceutical intermediates. It is particularly sought after by research chemists and process development teams in the fine chemical and life sciences sectors. Bromocyanoacetylene CAS NO 3114-46-3 enables efficient, convergent synthetic routes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Serves as an electrophilic partner in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Chemistry: Fundamental starting material for the construction of pyrazoles, isoxazoles, and other nitrogen-containing heterocycles.
• Chemical Biology Probes: Utilized in click chemistry and bioconjugation strategies to label biomolecules for study.

Basic Information

Product Name	Bromocyanoacetylene
CAS No.	3114-46-3
Molecular Formula	C3BrN
Molecular Weight	129.93 g/mol
Synonyms	2-Bromo-2-propynenitrile; Bromopropiolonitrile; 3-Bromopropynenitrile; Bromo(cyano)acetylene; Propiolonitrile, 3-bromo-; Bromocyanoethyne; 2-Propynenitrile, 3-bromo-
EINECS	221-476-9

Quality Control

Our Bromocyanoacetylene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity and NMR confirmation, to support your R&D and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with every shipment, and custom purity grades or analytical packages are available upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and light-sensitive nature, store in a cool (2-8°C), dry, and well-ventilated place, preferably under an inert atmosphere. Keep away from heat, sparks, and open flame. Allow the container to reach ambient temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.