Description

1,2,3-Trichloro-5-Fluorobenzene is a halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules where precise halogen positioning is critical. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated benzene core.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized aryl groups into more complex structures.
• Polymer Modification: Acts as a monomer or modifier in the production of specialty polymers with enhanced properties like chemical resistance.
• Dyestuff & Pigment Intermediate: Utilized in the synthesis of complex, high-performance dyes and pigments.

Basic Information

Product Name	1,2,3-Trichloro-5-Fluorobenzene
CAS No.	3107-21-9
Molecular Formula	C6H2Cl3F
Molecular Weight	199.44 g/mol
Synonyms	5-Fluoro-1,2,3-trichlorobenzene; 1,2,3-Trichloro-5-fluorobenzene; Benzene, 1,2,3-trichloro-5-fluoro-; 3,4,5-Trichlorofluorobenzene; FCB-235 (common abbreviation); 2,3,4-Trichlorofluorobenzene (alternate numbering); 1-Fluoro-2,3,4-trichlorobenzene
EINECS	221-465-5

Quality Control

Our 1,2,3-Trichloro-5-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and metals. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0% (Typical 99.0%)
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.