Description

n-(Acetoacetyl)Glycine is a versatile chemical building block and intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both acetoacetyl and glycine moieties, makes it a valuable precursor for the development of pharmaceuticals, fine chemicals, and specialized polymers. This compound is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and research sectors seeking to create novel compounds with specific functional properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific peptide-like or β-ketoamide functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its reactive groups enable targeted molecular design.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker or spacer molecule in bioconjugation techniques for drug delivery systems, diagnostics, and proteomics research.
• Polymer & Resin Modifier: Acts as a cross-linking agent or functional monomer to introduce specific chemical properties into specialty polymers, coatings, and adhesives.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Fine Chemical Production: Intermediate in the manufacture of complex fine chemicals, dyes, and photographic chemicals.

Basic Information

Product Name	n-(Acetoacetyl)Glycine
CAS No.	3103-38-6
Molecular Formula	C6H9NO4
Molecular Weight	159.14 g/mol
Synonyms	Acetoacetylglycine; N-Acetoacetylglycine; 3-Oxobutanoylaminoacetic Acid; (Acetoacetamido)acetic Acid; 2-[(3-Oxobutanoyl)amino]acetic Acid; Glycine, N-acetoacetyl-; Butanamide, N-(carboxymethyl)-3-oxo-
EINECS	221-450-5

Quality Control

Our n-(Acetoacetyl)Glycine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, IR, and titration methods, to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.