Description

γ-Glutamylmethylamide is a naturally occurring amino acid derivative and a key intermediate in the biosynthesis of theanine. This compound matters for its role in the production of L-theanine, a prominent nutraceutical and food additive prized for its relaxing properties. Industries that need it include manufacturers of dietary supplements, functional foods and beverages, and pharmaceutical intermediates, where it serves as a crucial building block for high-value bioactive ingredients.

Application

• Primary Intermediate for L-Theanine Synthesis: The most significant commercial application, serving as the direct precursor in enzymatic or chemical synthesis routes to produce high-purity L-theanine.
• Nutraceutical & Dietary Supplement Formulation: Used in the research and development of novel calming and cognitive health supplements.
• Functional Food & Beverage Enhancement: Incorporated into products like teas, drinks, and snacks designed to promote relaxation without drowsiness.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex neuroactive compounds and potential drug candidates.
• Biochemical Research: Utilized as a standard or reagent in studies of glutamine metabolism, enzyme kinetics (e.g., glutaminase), and neurotransmitter pathways.
• Cosmetic Ingredients: Explored for use in skincare formulations targeting stress-related skin conditions due to its connection to calming amino acids.

Basic Information

Product Name	γ-Glutamylmethylamide
CAS No.	3081-62-7
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	L-γ-Glutamylmethylamide; γ-Glutamylmethylamide; Glutamine Methylamide; Theanine Intermediate; N5-Methyl-L-glutamine; L-γ-Glutamylmethylamide; (S)-2-Amino-4-(methylcarbamoyl)butanoic acid; GMA
EINECS	221-369-6

Quality Control

Our γ-Glutamylmethylamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for nutraceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, residual solvents, and heavy metals is provided with every shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.