Description

4-Iodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a cyano group, makes it a critical precursor for constructing complex molecules via cross-coupling reactions and functional group transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to develop active ingredients and novel functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	4-Iodobenzonitrile
CAS No.	3058-39-7
Molecular Formula	C7H4IN
Molecular Weight	229.02 g/mol
Synonyms	p-Iodobenzonitrile; 4-Cyanoidobenzene; 1-Iodo-4-cyanobenzene; Benzonitrile, 4-iodo-; 4-Iodophenyl cyanide; p-Cyanoidobenzene; ICN-Ph-I (abbrev.); 3058-39-7 (CAS)
EINECS	221-300-4

Quality Control

Our 4-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	115°C - 118°C
Heavy Metals	≤20 ppm
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.