Description

2-(Trifluoromethyl)Phenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique electronic and lipophilic properties to target molecules, enhancing their metabolic stability and bioavailability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Advanced Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in various coupling reactions and as a starting material for synthesizing complex fluorinated compounds in academic and industrial R&D.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference standard or probe in analytical chemistry due to its distinct fluorine signature.

Basic Information

Product Name	2-(Trifluoromethyl)Phenylacetic Acid
CAS No.	3038-48-0
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	α-(Trifluoromethyl)phenylacetic Acid; 2-(Trifluoromethyl)benzeneacetic Acid; (2-Trifluoromethylphenyl)acetic Acid; o-(Trifluoromethyl)phenylacetic Acid; 2-(Trifluoromethyl)benzenecarboxylic Acid (common misnomer); 2-TFM-PAA; α-Trifluoromethylphenylacetic Acid
EINECS	221-247-5

Quality Control

Our 2-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.