Description

2-Fluoro-4-Methylanisole is a versatile fluorinated aromatic ether, serving as a key building block in advanced organic synthesis. This compound is valued for its ability to introduce both fluorine and methoxy substituents into molecular frameworks, enabling the fine-tuning of physical, chemical, and biological properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex aromatic systems for material science applications.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing specific fluorinated aromatic compounds used in high-value fragrance formulations.

Basic Information

Product Name	2-Fluoro-4-Methylanisole
CAS No.	399-55-3
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	1-Fluoro-2-Methoxy-5-Methylbenzene; 2-Fluoro-4-Methyl-1-Methoxybenzene; 4-Methyl-2-Fluoroanisole; 2-Fluoro-p-Cresol Methyl Ether; 5-Methyl-2-Fluoroanisole; Benzene, 1-fluoro-2-methoxy-5-methyl-; 2-Fluoro-4-methylphenyl methyl ether
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.10 g/cm³
Refractive Index (n20D)	~1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.