Description

4-Fluoro-1-Methoxy-2-Methylbenzene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of fluorine and methoxy substituents into complex molecular architectures. It is critically needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including engineering plastics and high-performance resins.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and exploring new reaction pathways in academic and industrial labs.
• Dye & Pigment Manufacturing: Intermediate for creating specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	4-Fluoro-1-Methoxy-2-Methylbenzene
CAS No.	399-54-2
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	2-Fluoro-4-Methoxytoluene; 4-Fluoro-2-Methylanisole; 1-Fluoro-2-Methoxy-5-Methylbenzene; 2-Methyl-4-Fluoroanisole; 4-Fluoro-o-Cresol Methyl Ether; p-Fluoro-o-Cresol Methyl Ether; 399-54-2; 4-Fluoro-2-methyl-1-methoxybenzene
EINECS	206-933-7

Quality Control

Our 4-Fluoro-1-Methoxy-2-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.08 g/cm³
Refractive Index (n20D)	~1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.