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2-(2,4-Difluorophenyl)Acetamide CAS NO 399-34-8


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CAS No.:399-34-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(2,4-Difluorophenyl)Acetamide is a high-purity fluorinated aromatic acetamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and stability.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antifungal, antibacterial, and central nervous system (CNS) drug candidates.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluorophenyl moiety contributes to improved activity and environmental profile.
  • Material Science Research: Acts as a precursor for specialty polymers, liquid crystals, and advanced materials that benefit from fluorine's unique electronic properties.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and other transformations to construct complex molecular architectures in medicinal and process chemistry.
  • Biochemical Research: Utilized as a probe or inhibitor in biochemical assays to study enzyme mechanisms and protein interactions.

Basic Information

Product Name 2-(2,4-Difluorophenyl)Acetamide
CAS No. 399-34-8
Molecular Formula C8H7F2NO
Molecular Weight 171.15 g/mol
Synonyms 2,4-Difluorophenylacetamide; α-(2,4-Difluorophenyl)acetamide; (2,4-Difluorophenyl)acetamide; 2,4-DFPA; NSC 403697; 2',4'-Difluoroacetophenone amide; Acetamide, 2-(2,4-difluorophenyl)-
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Quality Control

Our 2-(2,4-Difluorophenyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 142 - 146 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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