Description

2',5'-Difluoroacetanilide is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for introducing difluorophenyl motifs into more complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from the stability and bioavailability imparted by fluorine atoms.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals where fluorinated aromatic units enhance thermal stability and chemical resistance.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new fluorination methodologies and catalytic processes.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2',5'-Difluoroacetanilide
CAS No.	398-90-3
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	N-(2,5-Difluorophenyl)acetamide; 2,5-Difluoroacetanilide; 1-Acetamido-2,5-difluorobenzene; Acetamide, N-(2,5-difluorophenyl)-; 2,5-Difluoro-N-phenylacetamide; 2',5'-Difluoracetanilid; 2,5-DFA
EINECS	Contact for details

Quality Control

Our 2',5'-Difluoroacetanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.