Description

1,2-Dimethoxy-4-Fluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy groups, which allows for precise modification of molecular properties in target compounds. This intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and other electronic devices.
• Chemical Research & Development: A valuable reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Dye & Pigment Industry: Acts as an intermediate for producing specialized fluorinated dyes with unique color fastness and properties.

Basic Information

Product Name	1,2-Dimethoxy-4-Fluorobenzene
CAS No.	398-62-9
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	4-Fluoro-1,2-dimethoxybenzene; 4-Fluoroveratrole; 1-Fluoro-2,3-dimethoxybenzene; Veratrole, 4-fluoro-; 2,3-Dimethoxyfluorobenzene; 398-62-9; 4-Fluorobenzene-1,2-diol dimethyl ether
EINECS	206-924-3

Quality Control

Our 1,2-Dimethoxy-4-Fluorobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.505 - 1.515
Density (g/mL at 20°C)	1.15 - 1.19

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.