Description

1-Fluoro-2,3-dimethoxybenzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy groups, which allows for selective functionalization and the introduction of unique electronic properties into target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzene core.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Ligand & Catalyst Development: Employed to create specialized ligands for catalysis, leveraging the electron-donating methoxy and electron-withdrawing fluorine substituents.
• Fine Chemical & Flavor/Fragrance Intermediate: Acts as a building block for complex, high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological studies in cross-coupling reactions and nucleophilic aromatic substitution.

Basic Information

Product Name	1-Fluoro-2,3-dimethoxybenzene
CAS No.	394-64-9
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	2,3-Dimethoxyfluorobenzene; 2-Fluoro-1,2-dimethoxybenzene; 1-Fluoro-2,3-dimethoxybenzene; 2,3-Dimethoxy-1-fluorobenzene; Fluoroveratrole; 2,3-Dimethoxyfluorobenzene; 394-64-9; Fluorinated veratrole
EINECS	206-906-1

Quality Control

Our 1-Fluoro-2,3-dimethoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability, though the product is stable at controlled room temperature for shorter periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.