Description

Pentafluoroethyl Phenyl Ketone is a high-purity fluorinated aromatic ketone, a key building block in advanced chemical synthesis. This compound is valued for its unique reactivity profile, particularly in introducing the pentafluoroethyl group into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, leveraging the fluorine effect to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the pentafluoroethyl moiety can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a key raw material for synthesizing fluorinated components in electronic display and lighting technologies.
• Specialty Polymer Modifier: Imparts specific properties like oil repellency, chemical resistance, and low surface energy to advanced polymeric materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex fluorinated molecules via reactions like Friedel-Crafts acylation and nucleophilic addition.
• Fluorinated Surfactant Precursor: Used in the manufacture of high-performance surfactants and surface treatment agents.

Basic Information

Product Name	Pentafluoroethyl Phenyl Ketone
CAS No.	394-52-5
Molecular Formula	C9H5F5O
Molecular Weight	224.13 g/mol
Synonyms	1-Phenyl-2,2,3,3,3-pentafluoro-1-propanone; 2,2,3,3,3-Pentafluoro-1-phenyl-1-propanone; Pentafluoroacetophenone; α,α,α,β,β-Pentafluoropropiophenone; Phenyl Pentafluoroethyl Ketone; C6H5COCF2CF3; Pentafluoroethyl Benzene Ketone; 1-Propanone, 2,2,3,3,3-pentafluoro-1-phenyl-
EINECS	206-912-8

Quality Control

Our Pentafluoroethyl Phenyl Ketone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical properties. Our quality commitment ensures material consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.