Description

β-Oxo-n-[2-(Trifluoromethyl)Phenyl]-Benzenepropanamide is a specialized organic compound featuring a trifluoromethylphenyl group, a structural motif that imparts unique physicochemical properties critical for advanced chemical synthesis. This compound serves as a valuable building block (synthon) and intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its distinct structure enables the introduction of specific functional groups to modulate biological activity, stability, and metabolic profiles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers with tailored properties like chemical resistance or specific optical characteristics.
• Organic Synthesis & Catalysis: Employed as a sophisticated reagent in multi-step synthetic routes, including cross-coupling reactions and the construction of complex heterocycles.
• Chemical Reference Standard: Utilized in analytical laboratories as a high-purity standard for method development, validation, and quality control in related chemical production.

Basic Information

Product Name	β-Oxo-n-[2-(Trifluoromethyl)Phenyl]-Benzenepropanamide
CAS No.	393-34-0
Molecular Formula	C16H12F3NO2
Molecular Weight	307.27 g/mol
Synonyms	3-Oxo-N-[2-(trifluoromethyl)phenyl]-3-phenylpropanamide; 1-[2-(Trifluoromethyl)phenylamino]-1-phenyl-1,3-propanedione; 3-Oxo-3-phenyl-N-[2-(trifluoromethyl)phenyl]propanamide; N-(2-Trifluoromethylphenyl)-3-oxo-3-phenylpropionamide; β-Oxo-β-phenyl-N-(α,α,α-trifluoro-o-tolyl)propionamide; Benzenepropanamide, β-oxo-N-[2-(trifluoromethyl)phenyl]-; 393-34-0; [2-(Trifluoromethyl)phenyl]carbamoyl phenyl ketone
EINECS	Contact for details

Quality Control

Our production of β-Oxo-n-[2-(Trifluoromethyl)Phenyl]-Benzenepropanamide adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our commitment to cGMP principles and regulatory compliance (REACH, TSCA) ensures a reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.