Description

3-Fluorooxaloacetate is a fluorinated derivative of oxaloacetate, a key intermediate in the Krebs cycle, offering unique reactivity for advanced chemical synthesis. This compound is valued for its role as a specialized building block in the development of novel pharmaceuticals and biochemical research tools. It is primarily sought by research institutions and chemical companies engaged in medicinal chemistry, metabolic pathway studies, and the synthesis of fluorinated bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly those targeting metabolic enzymes.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of citrate synthase and related metabolic pathways.
• Medicinal Chemistry: Provides a versatile scaffold for introducing fluorine atoms into complex molecules to modulate their bioavailability and metabolic stability.
• Organic Synthesis: Acts as a fluorinated electrophile or a dicarbonyl component in various condensation and cyclization reactions.
• Metabolite Analog: Employed in cellular and microbiological studies to probe the effects of fluorinated metabolites on cell growth and metabolism.

Basic Information

Product Name	3-Fluorooxaloacetate
CAS No.	392-47-2
Molecular Formula	C4H3FO5
Molecular Weight	150.06 g/mol
Synonyms	3-Fluorooxaloacetic Acid; 3-Fluorooxobutanedioic Acid; 2-Oxo-3-fluorobutanedioic Acid; 3-Fluoro-2-oxosuccinic Acid; Oxaloacetic Acid 3-Fluoro Derivative; Fluoroxaloacetate; 3-FOA
EINECS	Contact for details

Quality Control

Our 3-Fluorooxaloacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at 2-8°C under desiccant. For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.