Description

2,3,4,5,6-Pentafluoroanisole is a highly fluorinated aromatic ether, a key building block in advanced chemical synthesis. Its unique structure, featuring a pentafluorophenyl group bonded to a methoxy substituent, makes it an invaluable intermediate for introducing fluorine atoms into target molecules. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging fluorine's ability to increase lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs), improving charge transport and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart desirable properties such as chemical resistance, low surface energy, and enhanced thermal stability.
• Fluorinated Surfactant & Coating Precursor: Acts as a starting material for synthesizing surfactants and surface treatment agents with superior oil and water repellency.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	2,3,4,5,6-Pentafluoroanisole
CAS No.	389-40-2
Molecular Formula	C7H3F5O
Molecular Weight	198.09 g/mol
Synonyms	Pentafluoroanisole; Methoxyperfluorobenzene; Perfluoroanisole; 2,3,4,5,6-Pentafluorophenyl methyl ether; 1-Methoxy-2,3,4,5,6-pentafluorobenzene; Anisole, pentafluoro-; NSC 9235
EINECS	206-873-6

Quality Control

Our 2,3,4,5,6-Pentafluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.