Description

N-(Trifluoroacetyl)Glycine is a high-purity trifluoroacetylated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a protected glycine moiety that is stable under various reaction conditions, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of novel peptides, active pharmaceutical ingredients (APIs), and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and complex active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and plant growth regulators.
• Peptide Chemistry: Serves as a protected glycine derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Organic Synthesis Building Block: Employed in the construction of heterocyclic compounds and other complex molecular architectures.
• Bioconjugation & Labeling: Useful in modifying biomolecules for research, diagnostics, and therapeutic applications.
• Material Science Research: Acts as a monomer or modifier in the development of specialized polymers and advanced materials.

Basic Information

Product Name	N-(Trifluoroacetyl)Glycine
CAS No.	383-70-0
Molecular Formula	C4H4F3NO3
Molecular Weight	171.07 g/mol
Synonyms	2-[(Trifluoroacetyl)amino]acetic Acid; Glycine, N-(trifluoroacetyl)-; Trifluoroacetylglycine; N-Trifluoroacetylglycine; TFA-Gly-OH; 2-(Trifluoroacetamido)acetic Acid; Acetic acid, 2-[(trifluoroacetyl)amino]-; NSC 5239
EINECS	206-847-5

Quality Control

Our N-(Trifluoroacetyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.