Description

n-Ethyl 4-Fluorobenzenesulfonamide is a specialized organosulfur compound featuring a fluorinated aromatic ring and an ethyl-substituted sulfonamide group. This structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for introducing the sulfonamide pharmacophore. It is primarily utilized by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients, where its fluorine atom and sulfonamide functionality are critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with specific surface properties.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in biochemical research for studying enzyme inhibition and protein interactions.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	n-Ethyl 4-Fluorobenzenesulfonamide
CAS No.	383-48-2
Molecular Formula	C8H10FNO2S
Molecular Weight	203.24 g/mol
Synonyms	4-Fluoro-N-ethylbenzenesulfonamide; p-Fluoro-N-ethylbenzenesulfonamide; N-Ethyl-4-fluorobenzenesulfonamide; Benzenesulfonamide, 4-fluoro-N-ethyl-; Ethyl(4-fluorophenyl)sulfonylamine
EINECS	Contact for details

Quality Control

Our n-Ethyl 4-Fluorobenzenesulfonamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.