Description

Propanenitrile, 3,3,3-Trifluoro-2-(Trifluoromethyl)- is a highly fluorinated nitrile building block, prized for its unique reactivity and ability to introduce trifluoromethyl groups into complex molecules. Its value lies in enabling the synthesis of advanced materials and pharmaceuticals with enhanced properties like metabolic stability and lipophilicity. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate with fluorine chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs) containing trifluoromethyl motifs, which can improve drug efficacy and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental stability.
• Fluorinated Polymer & Material Science: Serves as a monomer or precursor for creating specialty polymers, coatings, and electronic materials with unique surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cyano-group transformation reactions to construct complex fluorinated organic molecules for research and scale-up.
• Liquid Crystal & OLED Material Development: Acts as a precursor in the synthesis of fluorinated components for display and lighting technologies, influencing dielectric anisotropy and performance.

Basic Information

Product Name	Propanenitrile, 3,3,3-Trifluoro-2-(Trifluoromethyl)-
CAS No.	382-17-2
Molecular Formula	C5H2F6N
Molecular Weight	190.07 g/mol
Synonyms	2-(Trifluoromethyl)-3,3,3-trifluoropropanenitrile; 3,3,3-Trifluoro-2-(trifluoromethyl)propanenitrile; 1,1,1,4,4,4-Hexafluoro-2-butanenitrile; Hexafluoroisobutyronitrile; HFIBN; Perfluoroisobutyronitrile; PFIBN; (Trifluoromethyl)trifluoroacetonitrile
EINECS	206-843-5

Quality Control

Our Propanenitrile, 3,3,3-Trifluoro-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed and at a stable temperature, ideally between 15-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.50 g/mL
Refractive Index (n20D)	~1.31

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.