Description

2-Trifluoromethyl Acrylonitrile is a versatile fluorinated building block characterized by its reactive nitrile and alkene functionalities. This compound is crucial for introducing the highly stable and lipophilic trifluoromethyl group into advanced molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as in materials science for creating specialty polymers and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced metabolic stability and bioavailability.
• Advanced Material Precursor: Serves as a monomer for synthesizing specialty fluoropolymers with unique surface properties, chemical resistance, and optical characteristics.
• Liquid Crystal & OLED Material Development: Employed in the research and production of fluorinated components for electronic displays and lighting.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, cycloadditions, and other transformations to construct complex fluorinated molecules.

Basic Information

Product Name	2-Trifluoromethyl Acrylonitrile
CAS No.	381-84-0
Molecular Formula	C4H2F3N
Molecular Weight	121.06 g/mol
Synonyms	2-(Trifluoromethyl)acrylonitrile; 3,3,3-Trifluoro-2-propenenitrile; 1,1,1-Trifluoro-2-cyanoethene; Trifluoromethylacrylonitrile; TFMAN; Acrylonitrile, 2-(trifluoromethyl)-; α-(Trifluoromethyl)acrylonitrile; 2-Propenenitrile, 3,3,3-trifluoro-
EINECS	206-838-5

Quality Control

Our 2-Trifluoromethyl Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed under an inert atmosphere to minimize moisture uptake and polymerization risk.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.