Description

Ethyl 2,2-Difluoro-3-Hydroxypropionate is a versatile fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique combination of a reactive ester group and a fluorinated hydroxypropionate moiety, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the introduction of fluorine atoms enhances metabolic stability and activity.
• Fluorinated Material Precursor: Serves as a monomer or intermediate for specialty polymers and materials with tailored surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and condensation reactions to introduce difluorohydroxypropionate units into complex molecular architectures.
• Liquid Crystal & Electronic Chemical Intermediate: Potential use in the synthesis of fluorinated components for display materials and electronic applications.

Basic Information

Product Name	Ethyl 2,2-Difluoro-3-Hydroxypropionate
CAS No.	380-41-6
Molecular Formula	C5H8F2O3
Molecular Weight	154.11 g/mol
Synonyms	2,2-Difluoro-3-hydroxypropionic Acid Ethyl Ester; Ethyl 2,2-Difluoro-3-hydroxypropanoate; 3-Hydroxy-2,2-difluoropropionic Acid Ethyl Ester; Ethyl 3-Hydroxy-2,2-difluoropropionate; Propanoic acid, 2,2-difluoro-3-hydroxy-, ethyl ester; Ethyl α,α-Difluoro-β-hydroxypropionate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-3-Hydroxypropionate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents. The container must be kept tightly closed to minimize moisture absorption from the air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.