Description

2,2,3,4,4,4-Hexafluorobutanoic Acid is a highly fluorinated short-chain carboxylic acid, valued for its strong acidity and the unique properties imparted by its fluorine atoms. This compound serves as a critical building block and reagent in advanced chemical synthesis, where its perfluorinated alkyl group introduces desirable characteristics like enhanced stability, lipophilicity, and surface activity. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Serves as a key precursor for creating fluorinated pesticides and herbicides with enhanced efficacy and environmental persistence.
• Polymer & Material Science: Acts as a monomer or modifier for producing fluoropolymers and surface-active agents with oil- and water-repellent properties.
• Catalyst & Ligand Preparation: Employed in the preparation of fluorinated catalysts and ligands for specialized organic transformations.
• Analytical Chemistry: Utilized as a derivatization agent or a standard in chromatographic analysis and mass spectrometry.
• Electronics Industry: Finds application in the etching and cleaning processes for semiconductor manufacturing.

Basic Information

Product Name	2,2,3,4,4,4-Hexafluorobutanoic Acid
CAS No.	379-90-8
Molecular Formula	C4H2F6O2
Molecular Weight	196.05 g/mol
Synonyms	Hexafluorobutyric Acid; Perfluorobutyric Acid; 2,2,3,4,4,4-Hexafluorobutanoic Acid; 4,4,4-Trifluoro-3-(trifluoromethyl)butanoic Acid; HFBA; PFBA; CF3CF2CHFCOOH; EINECS 206-818-5
EINECS	206-818-5

Quality Control

Our 2,2,3,4,4,4-Hexafluorobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and strong acid nature, the container must be kept tightly sealed in a dry environment and separated from strong bases and incompatible materials. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.300 - 1.320
Density (20°C)	1.60 - 1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.