Description

18-Hydroxy-11-Deoxycorticosterone is a key intermediate in the synthesis of various steroid hormones. This compound is of significant value in pharmaceutical research and development, particularly for studying adrenal cortex function and related metabolic pathways. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for the production of reference standards and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical synthesis building block for corticosteroid and mineralocorticoid APIs.
• Biochemical Research: Used as a reference standard and reagent in studies of steroidogenesis and adrenal gland function.
• Metabolic Pathway Analysis: Employed in laboratory investigations to understand hormone biosynthesis and regulation.
• Reference Material Production: Serves as a high-purity starting material for manufacturing certified reference standards (CRS).
• Life Science Reagent: Utilized in enzymatic assays and other in-vitro diagnostic (IVD) development applications.

Basic Information

Product Name	18-Hydroxy-11-Deoxycorticosterone
CAS No.	379-68-0
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	18-Hydroxydeoxycorticosterone; 18-OH-DOC; 11-Deoxy-18-hydroxycorticosterone; 18,21-Dihydroxypregn-4-ene-3,20-dione; 18-Hydroxy-11-deoxycorticosterone; 18-Hydroxy-DOC; 18-Hydroxycortexone; 18-Hydroxy-21-hydroxypregn-4-ene-3,20-dione
EINECS	206-806-1

Quality Control

Our 18-Hydroxy-11-Deoxycorticosterone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.