Description

Sodium Pentafluoropropionate CAS NO 378-77-8 is a specialized fluorinated organic salt that serves as a key building block in advanced chemical synthesis. Its unique structure, featuring a perfluorinated alkyl chain, makes it a valuable precursor for introducing trifluoromethyl and pentafluoroethyl groups into target molecules, significantly altering their physical and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity fluorinated intermediates to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethyl or pentafluoroethyl groups, which can enhance metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where fluorination is key to improving efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the production of specialty polymers, surfactants, and coatings to impart oil/water repellency, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystals and electronic chemicals for displays and semiconductor applications.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in nucleophilic trifluoromethylation and perfluoroalkylation reactions under various catalytic conditions.
• Research & Development: A valuable tool for medicinal chemistry and chemical biology research for probing structure-activity relationships and developing diagnostic agents.

Basic Information

Product Name	Sodium Pentafluoropropionate
CAS No.	378-77-8
Molecular Formula	C3F5NaO2
Molecular Weight	193.99 g/mol
Synonyms	Sodium 2,2,3,3,3-Pentafluoropropionate; Pentafluoropropionic Acid Sodium Salt; 2,2,3,3,3-Pentafluoropropanoic Acid Sodium Salt; Sodium Perfluoropropionate; NaPFP; CF3CF2COONa
EINECS	206-828-5

Quality Control

Our Sodium Pentafluoropropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry atmosphere to prevent degradation. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.