Description

Methyl 2-Bromo-2,3,3,3-Tetrafluoropropionate is a versatile fluorinated building block and reagent of significant interest in advanced organic synthesis. Its value lies in its ability to introduce both bromine and multiple fluorine atoms into target molecules, enabling the precise construction of complex, high-value compounds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries who require reliable, high-purity intermediates for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms are used to modulate metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, insecticides, and fungicides that incorporate fluorine for enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, where fluorine substitution improves thermal stability, dielectric anisotropy, and optical properties.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, imparting valuable characteristics such as oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis Reagent: Functions as an electrophilic reagent for introducing the -CF2Br or -CF3 moiety via subsequent transformations, valuable in medicinal chemistry and material science.

Basic Information

Product Name	Methyl 2-Bromo-2,3,3,3-Tetrafluoropropionate
CAS No.	378-67-6
Molecular Formula	C4H3BrF4O2
Molecular Weight	222.96 g/mol
Synonyms	2-Bromo-2,3,3,3-tetrafluoropropionic Acid Methyl Ester; Methyl α-Bromo-α,β,β,β-tetrafluoropropionate; Methyl 2-Bromo-2,3,3,3-tetrafluoropropanoate; 2-Bromo-2,3,3,3-tetrafluoropropanoic Acid Methyl Ester; Bromotetrafluoropropionic Acid Methyl Ester; MeO2CCFBrCF3; Methyl Bromotetrafluoropropionate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-2,3,3,3-Tetrafluoropropionate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is fully characterized and undergoes rigorous analytical testing, including GC, HPLC, and NMR, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to the presence of fluoride and bromine, handle with appropriate personal protective equipment and ensure compatibility with storage container materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.