Description

2,2,3,3-Tetrafluoro-3-(Heptafluoropropoxy)Propionic Acid is a high-purity fluorinated organic acid, a key intermediate in advanced chemical synthesis. Its unique perfluorinated ether chain and carboxylic acid functionality make it a versatile building block for creating compounds with exceptional chemical and thermal stability. This product is essential for R&D and manufacturing in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required to modify solubility, bioavailability, or surface properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorinated structure contributes to improved efficacy and environmental persistence profiles.
• Fluorinated Surfactant & Polymer Production: Acts as a monomer or modifier in the creation of specialty fluorosurfactants and high-performance polymers for coatings, electronics, and aerospace applications.
• Lithium-Ion Battery Electrolyte Additive: Employed in the formulation of advanced electrolyte salts and additives to improve battery cycle life, safety, and performance at extreme temperatures.
• Organic Synthesis Reagent: Functions as a strong, fluorinated acid catalyst or a building block in complex organic transformations, including nucleophilic substitution and esterification reactions.
• Surface Treatment & Functionalization: Used to modify material surfaces to achieve oil-, water-, and stain-repellent characteristics for textiles and industrial materials.

Basic Information

Product Name	2,2,3,3-Tetrafluoro-3-(Heptafluoropropoxy)Propionic Acid
CAS No.	378-03-0
Molecular Formula	C6HF11O3
Molecular Weight	330.05 g/mol
Synonyms	Perfluoropropoxypropanoic Acid; 3-(Heptafluoropropoxy)-2,2,3,3-tetrafluoropropionic Acid; 2,2,3,3-Tetrafluoro-3-(perfluoropropoxy)propanoic Acid; HFP-TFPA; PFP-TFPA; 3-(1,1,2,2,3,3,3-Heptafluoropropoxy)-2,2,3,3-tetrafluoropropionic Acid; TFHPA; Heptafluoropropyl 2,2,3,3-tetrafluoro-3-propionate
EINECS	206-817-5

Quality Control

Our production of 2,2,3,3-Tetrafluoro-3-(Heptafluoropropoxy)Propionic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed to prevent moisture absorption and potential corrosion. Recommended long-term storage temperature is between 2°C and 8°C to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.