Description

Tetrafluorosuccinic Acid CAS NO 377-38-8 is a highly fluorinated dicarboxylic acid derivative, characterized by its strong acidity and unique chemical reactivity. This compound serves as a critical fluorinated building block and intermediate in advanced organic synthesis, enabling the introduction of fluorine atoms to enhance material properties. It is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel fluorinated compounds with improved stability, bioavailability, or surface activity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs, leveraging fluorine's metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides, where fluorine atoms can increase lipophilicity and biological activity.
• Polymer & Material Science: Serves as a monomer or modifier for creating fluorinated polyesters, polyamides, and coatings with enhanced chemical resistance, thermal stability, and low surface energy.
• Ligand & Catalyst Preparation: Employed in the synthesis of fluorinated ligands for metal complexes used in catalysis and material design.
• Organic Synthesis Reagent: Acts as a strong acidic catalyst or a versatile difunctional reagent in various fluorination and condensation reactions.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.

Basic Information

Product Name	Tetrafluorosuccinic Acid
CAS No.	377-38-8
Molecular Formula	C4H2F4O4
Molecular Weight	190.05 g/mol
Synonyms	Perfluorosuccinic Acid; 2,2,3,3-Tetrafluorosuccinic Acid; Tetrafluorobutanedioic Acid; Difluorofumaric Acid Dihydrate (related); Perfluorobutanedioic Acid; NSC 9235; 1,2,2,3-Tetrafluorosuccinic Acid; Succinic Acid, Tetrafluoro-
EINECS	206-828-5

Quality Control

Our Tetrafluorosuccinic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.