Description

Nonafluorobutanesulfonyl Fluoride is a highly versatile perfluorinated sulfonyl fluoride building block, essential for introducing the nonafluorobutanesulfonyl (nonaflate) group into target molecules. Its primary value lies in its exceptional reactivity as a precursor for nonaflate salts and esters, which serve as superior alternatives to triflate in various synthetic transformations. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for advanced synthesis and catalysis.

Application

• Pharmaceutical Intermediate Synthesis: Key precursor for nonaflate (Nf) salts and esters, used as superior leaving groups in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions.
• Agrochemical Manufacturing: Employed in the synthesis of advanced active ingredients, where the nonaflate group enhances metabolic stability and bioavailability.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating fluorinated polymers with unique surface properties, such as oil/water repellency and chemical resistance.
• Catalyst & Ligand Preparation: Used to synthesize specialized fluorinated ligands and organocatalysts for use in demanding reaction environments.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.
• Surface Modification: Applied to create self-assembled monolayers (SAMs) or to fluorinate surfaces for specific electronic or hydrophobic applications.

Basic Information

Product Name	Nonafluorobutanesulfonyl Fluoride
CAS No.	375-72-4
Molecular Formula	C4F10O2S
Molecular Weight	302.09 g/mol
Synonyms	Perfluorobutanesulfonyl Fluoride; 1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonyl Fluoride; Nonaflate Fluoride; Nf-F; Nonafluorobutanesulfonic Acid Fluoride; Nonafluorobutylsulfonyl Fluoride; Nonaflyl Fluoride; 4,4,4,3,3,2,2,1,1-Nonafluorobutanesulfonyl Fluoride
EINECS	206-793-1

Quality Control

Our Nonafluorobutanesulfonyl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.