Description

1,1,1-Trifluoro-2-Propanol is a versatile fluorinated alcohol characterized by its unique combination of a hydroxyl group and a trifluoromethyl moiety. This structure makes it a valuable intermediate and solvent in advanced chemical synthesis, offering enhanced reactivity and stability in demanding processes. It is particularly sought after by manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise fluorination or high-performance solvent properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating fluorine for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Specialty Solvent: Serves as a high-performance solvent for resins, polymers, and in electrochemical applications due to its strong acid/organic solvent compatibility and high volatility.
• Fluorinated Polymer Production: Acts as a monomer or modifier in the synthesis of specialty fluoropolymers, imparting desirable properties like chemical resistance and low surface energy.
• Laboratory Reagent: Employed in research and development for organic synthesis, particularly in nucleophilic substitution and esterification reactions facilitated by its activated hydroxyl group.
• Electronics Industry: Used in the formulation of cleaning agents and etching solutions for precision electronic components.

Basic Information

Product Name	1,1,1-Trifluoro-2-Propanol
CAS No.	374-01-6
Molecular Formula	C3H5F3O
Molecular Weight	114.07 g/mol
Synonyms	2,2,2-Trifluoro-1-methylethanol; 1,1,1-Trifluoroisopropanol; TFIP; 2-Propanol, 1,1,1-trifluoro-; 2-Hydroxy-1,1,1-trifluoropropane; α-Trifluoromethyl ethanol; 1-Methyl-2,2,2-trifluoroethanol
EINECS	206-779-0

Quality Control

Our 1,1,1-Trifluoro-2-Propanol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC, water content (KF), and impurity profiling, to ensure it meets the high-purity standards required for industrial and research applications. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, containers must be kept tightly sealed and away from heat, sparks, and open flame. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	1.280 - 1.290 g/mL
Refractive Index (n20D)	1.300 - 1.310

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.